GENETIC (HEREDITARY)

Depressive Disease can run in the families. The parents, siblings and children of a depressed person are at a higher risk of developing clinically diagnosable Depressive Disease than those persons who do not have a depressed patient in their families.

Risk of Developing Depressive disease:

• General Population= 3%
• If one person has Depressive Disease then other siblings= 13%
• Parents= 15%
• Children when one parent has Depressive Disease= 20%
• Children when both parents have Depressive Disease.= 50%
• Monozygotic twins= 70%

Certain chromosomes have been implicated in the transmission of the Depressive Disease. The chromosomes carry the gene, which makes the person predisposed for Depressive Disease.

| Genetic | Bio-chemical | Psychological | Social factors |