ALPHA FETO PROTEIN (AFP)

SCREENING FOR FETAL DEFECTS AND FETAL DISEASE DURING PREGNANCY

Maybe used alone but, generally used in combination with Beta-hCG and uE3 as triple marker test for evaluation of fetal well being and detection of genetic fetal defects early in the pregnancy. (details given in the section on Triple Marker-2^nd Trimester)

TUMOR MARKER FOR TUMORS

1. AFP in combination with hCG forms a major tool in detecting and differential diagnosis of the tumors of testes and ovary.
2. It is an important marker for Liver cancers.
3. Is used for monitoring treatment for recurrence and progression of the tumors. It also correlates with tumor volume (size).